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Researchers of the Zelinsky Institute discovered a new reactivity of pyridinium ylides
12 september 2022 г.
Researchers of the Zelinsky Institute discovered a new reactivity of pyridinium ylides
N-substituted ylides are versatile building blocks in organic synthesis, widely used to construct nitrogen-containing heterocycles. In particular, pyridinium…
ZIOC scientists have proposed an effective method for the synthesis of sterically hindered acridines
8 september 2022 г.
ZIOC scientists have proposed an effective method for the synthesis of sterically hindered acridines
The processes occurring under photoredox catalysis conditions are currently being actively studied all over the world. Most often they proceed in mild…
Researchers of the ZIOC published a review on [4+1]-annulation reactions
5 september 2022 г.
Researchers of the ZIOC published a review on [4+1]-annulation reactions
Five-membered heterocycles containing one or more heteroatoms are important intermediates in organic synthesis on the way to bioactive and natural compounds.…
An unusual cyclization leading to functionalized isoxazolines was discovered at ZIOC
1 september 2022 г.
An unusual cyclization leading to functionalized isoxazolines was discovered at ZIOC
Isoxazolines are important representatives of five-membered nitrogen-oxygen heterocycles widely used in organic and medicinal chemistry. The isoxazoline…
Scientists from the Zelinsky Institute have developed an approach to the synthesis of important heterocyclic compounds
24 august 2022 г.
Scientists from the Zelinsky Institute have developed an approach to the synthesis of important heterocyclic compounds
Functionalized derivatives of malonic ester are widely used in the synthesis of complex carbocyclic compounds. Their advantages are the ease of preparation,…
Scientists from the Zelinsky Institute have developed a stereoselective method for 1,2-cis-glucosylation
18 august 2022 г.
Scientists from the Zelinsky Institute have developed a stereoselective method for 1,2-cis-glucosylation
Fragments of 1,2-cis-linked glucose are a part of many biologically significant oligosaccharides. Traditionally, glucosyl donors containing a non-participating…
A new safe source of hydrazoic acid has been developed with the participation of ZIOC
10 august 2022 г.
A new safe source of hydrazoic acid has been developed with the participation of ZIOC
In recent decades, alkyl azides have attracted increasing interest due to the possibility of their application both in organic synthesis and as high-energy…
Scientists from the ZIOC have proposed an updated «isoxazoline route» for the synthesis of aldols
3 august 2022 г.
Scientists from the ZIOC have proposed an updated "isoxazoline route" for the synthesis of aldols
Aldol condensation is one of the most common and widely used transformations to construct carbon-carbon bonds. However, versatile regio- and diastereoselective…
Pd/NHC complexes containing fluorine atoms were synthesized at the Zelinsky Institute
25 july 2022 г.
Pd/NHC complexes containing fluorine atoms were synthesized at the Zelinsky Institute
Complexes metal/N-heterocyclic carbene (NHC) have been actively used in recent years in various catalytic reaction. They managed to prove themselves excellently…
Researchers from the Zelinsky Institute have published a chapter in the book “Heterocycles: Synthesis, Catalysis, Sustainability, and Characterization”
21 july 2022 г.
Researchers from the Zelinsky Institute have published a chapter in the book “Heterocycles: Synthesis, Catalysis, Sustainability, and Characterization”
Heterocyclic compounds occupy an important place in our daily life — they are used in fine organic synthesis, pharmaceuticals, and agriculture. A significant…