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2014-01-01 13:02:00

Synthesized oligosaccharide, which is the active component of innovative vaccine

Synthesized oligosaccharide, which is the active component of innovative vaccine

In chemistry lab glycoconjugates Zelinsky Institute headed Corr. RAS Nicholas E. Nifant’eva was synthesized unique oligosaccharide, which is an active component of innovative vaccines.

Vaccine, the effect of which was studied at Harvard Medical School, can be used to combat Staphylococcus aureus and other dangerous bacteria, fungi, and protozoa.

The results were published in the journal «Proceedings of the National Academy of Sciences of the United States of America, 2013, may, doi: 10.1073/pnas.1303573110," Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens".

Professional community assessed the results as a breakthrough in the protection from exposure to dangerous pathogens. Congratulations on the success of our colleagues who participated in this work: Nicholas Nifant’eva, Yuri Tsvetkov, Marina Gening.

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Important events:

Professor Mario Pargliaro Lecturing at Zelinsky Institute Prof Mario Pagliaro (Palermo Italy) gave two talks on June 8th and 9th.
Selective In-Situ Metal Azide Reactions Alexey Sukhorukov, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia, and colleagues studied the selective reactions of in-situ generated metal azides on N,N-bis(oxy)enamines. By combining readily generated bis(oxy)enamine substrates with sodium azide and one of a variety of metal salts (including Mg, Cu, Zn, Co, and Ni), the researchers showed that the metal cation selectively alters the mechanism to favor the formation of specific organoazide products.
On February 1st, Prof. Gleb Sukhorukov from the School of Engineering and Materials Science, Queen Mary, University of London, gave a lecture “Remote Controlled Delivery Nanosystems” at ZIOC.
“We can record up to one thousand spectra per day” Director of Zelinsky Institute about Devising New Molecules
Steep and Thorny Way of a Scientist in Russia Prof. Valentine Ananikov participated in the plenary panel discussion HR Challenge for the Society held in the framework of VII Russian National Congress of Young Scientists and Specialists on November 30 – December 1 2016 in MEPhI.
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