Head: Victor V. Semenov, DSc (Chem.) (e-mail: vsioc.ac.ru, tel.: +7(499) 135-6343)
The laboratory was established in 1961 and headed by Dr. N.F. Kononov (1961-1979) and by Prof. S.Z. Taits (1980-1989).
Processing technology for the simplest natural raw materials (carbon dioxide, acetylene, isoprenoids, and cellulose) and waste from chemical industry (chloroaromatic, hydrogen fluoride and nitro compounds);
Synthesis of analogs and precursors of natural heterocyclic compounds (five- and six-member nitrogen heterocycles) and isoprenoids based on original technologies with the use of high pressure and temperature, gaseous acetylene and ammonia, and hydrogenation on heterogeneous catalysts.
A continually replenished collection of chemical compounds (>150,000) was created for their screening against certain types of anti-tumor activity using original test systems;
NMR, MS and IR databases were developed along with a procedure of a rapid structural search of molecules in chemical literature and commercial databases;
Laboratory’s R&D products are in demand ln more than 150 chemical companies, including world leaders such as Glaxo, BASF, Bayer, Novartis, NovoNordisk, DuPont, Astra Zeneca, Pfizer, etc.