Leninsky Prospect, 47, Moscow
Phone: +7 499 137-29-44
Fax: +7 499 135-53-28

Laboratory of Medicinal Chemistry (N17)

Head: Victor V. Semenov, DSc (Chem.) (e-mail: vsioc.ac.ru, tel.: +7(499) 135-6343)

The laboratory was established in 1961 and headed by Dr. N.F. Kononov (1961-1979) and by Prof. S.Z. Taits (1980-1989).

Research Areas

Processing technology for the simplest natural raw materials (carbon dioxide, acetylene, isoprenoids, and cellulose) and waste from chemical industry (chloroaromatic, hydrogen fluoride and nitro compounds);

Synthesis of analogs and precursors of natural heterocyclic compounds (five- and six-member nitrogen heterocycles) and isoprenoids based on original technologies with the use of high pressure and temperature, gaseous acetylene and ammonia, and hydrogenation on heterogeneous catalysts.

Лаборатория 17

Main Results

A continually replenished collection of chemical compounds (>150,000) was created for their screening against certain types of anti-tumor activity using original test systems;

NMR, MS and IR databases were developed along with a procedure of a rapid structural search of molecules in chemical literature and commercial databases;

Laboratory’s R&D products are in demand ln more than 150 chemical companies, including world leaders such as Glaxo, BASF, Bayer, Novartis, NovoNordisk, DuPont, Astra Zeneca, Pfizer, etc.

Conferences organized by Institute:

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Important events:

Professor Mario Pargliaro Lecturing at Zelinsky Institute Prof Mario Pagliaro (Palermo Italy) gave two talks on June 8th and 9th.
Selective In-Situ Metal Azide Reactions Alexey Sukhorukov, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia, and colleagues studied the selective reactions of in-situ generated metal azides on N,N-bis(oxy)enamines. By combining readily generated bis(oxy)enamine substrates with sodium azide and one of a variety of metal salts (including Mg, Cu, Zn, Co, and Ni), the researchers showed that the metal cation selectively alters the mechanism to favor the formation of specific organoazide products.
On February 1st, Prof. Gleb Sukhorukov from the School of Engineering and Materials Science, Queen Mary, University of London, gave a lecture “Remote Controlled Delivery Nanosystems” at ZIOC.
“We can record up to one thousand spectra per day” Director of Zelinsky Institute about Devising New Molecules
Steep and Thorny Way of a Scientist in Russia Prof. Valentine Ananikov participated in the plenary panel discussion HR Challenge for the Society held in the framework of VII Russian National Congress of Young Scientists and Specialists on November 30 – December 1 2016 in MEPhI.
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