Leninsky Prospect, 47, Moscow
Phone: +7 499 137-29-44
Fax: +7 499 135-53-28
2020-06-30 15:36:00

Russian Scientists Discovered a New Class of Fungicides for Plant Protection and Crop Preservation

The substances based on stable organic peroxides not only exhibit high antifungal activity but also are safe for pollinating insects.

«None of the fungicides currently used for plant protection and crop preservation contains a peroxide moiety. A new class of fungicides was last time discovered in the 90s – these were strobilurins, and triazoles have been in use since as long ago as the 70s. Understanding of chemistry may let one think that peroxides are unstable and hazardous, and therefore are not useful. However, we developed compounds which are related to stable natural artemisinin peroxide. It and its derivatives are applied in medical practice to treat malaria. Moreover, they exhibit antiparasitic, anti-cancer, anti-tuberculosis and antiviral activity.” – says a senior researcher of ZIOC, PhD Ivan Yaremenko.

A research team led by Mikhail Syromyatnikov, an associate professor of Voronezh State University, conducted toxicity tests for pollinating insects. For that, they fed bumblebees with sugar syrup and studied the effect occurring at contact with fungicidal solutions. Cyclic peroxides proved nontoxic for bumblebees. They did not have adverse effect on the pollinating insect and its flying and, hence, pollinating activity.

Dr. Ivan A. Yaremenko, Peter S. Radulov, Yulia Y. Belyakova, Arina A. Demina, Dmitriy I. Fomenkov, Dr. Denis V. Barsukov, Dr. Irina R. Subbotina, Prof. Fabrice Fleury, Prof. Alexander O. Terent'ev    Cover Feature: Catalyst Development for the Synthesis of Ozonides and Tetraoxanes Under Heterogeneous Conditions: Disclosure of an Unprecedented Class of Fungicides for Agricultural Application (Chem. Eur. J. 21/2020) DOI: 10.1002/chem.202000923

Ivan A. Yaremenko, Mikhail Y. Syromyatnikov, Peter S. Radulov, Yulia Yu. Belyakova, Dmitriy I. Fomenkov, Vasily N. Popov, Alexander O. Terent’ev  Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic Fungus Ascosphaera apis without Toxic Effect on Bumblebees (Molecules 2020) DOI: 10.3390/molecules25081954

Important events:

The European Academy of Sciences (Academia Europaea) was founded in 1988. It unites about four thousand globally acknowledged experts in mathematics, medicine, natural sciences, humanities, law, economy, and social and political sciences from many countries of Europe. Among its members are also European scientists who live in other regions of the world. Currently, it includes seventy two Nobel laureates and it should be highlighted that many of them were elected to the Academy before winning the Prize.
Prof Mario Pagliaro (Palermo Italy) gave two talks on June 8th and 9th.
Alexey Sukhorukov, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia, and colleagues studied the selective reactions of in-situ generated metal azides on N,N-bis(oxy)enamines. By combining readily generated bis(oxy)enamine substrates with sodium azide and one of a variety of metal salts (including Mg, Cu, Zn, Co, and Ni), the researchers showed that the metal cation selectively alters the mechanism to favor the formation of specific organoazide products.
All Events »