Laboratory of supramolecular chemistry (№2)
Head of the Laboratory — Prof., Dr. Sci. Sergey Z. Vatsadze
e-mail: zurabych@gmail.com
The main direction of the work of the Laboratory is research in the field of supramolecular chemistry, namely, the design, synthesis and study of new molecules as components of functional supramolecular assemblies and materials based on them, as well as the use of supramolecular approaches in organic chemistry, medicinal chemistry and organic materials science including:
– synthesis of polydentate polyheterocyclic compounds including chiral macrocyclic and macropolycyclic ones as selective receptors and catalysts;
– detailed study of the interaction of synthetic and natural molecules with natural and synthetic receptors by experimental and theoretical methods;
– study of the fundamental role of intermolecular interactions in the context of the study of the mechanisms of organic reactions including the study of stereoelectronic effects by calculation and experimental methods;
– development of systems for selective delivery and controlled release of drugs and agrochemicals based on complexes of the inclusion of active molecules in the cavity of macrocyclic receptors;
– development of bioimaging tools using complexes of lanthanides and luminescent organic molecules and photophysical materials based on them;
– synthesis and study of supramolecular polymers including gels, metallogels, metal-organic frameworks, supramolecular organic frameworks, covalent organic frameworks; study of photochemical, sorption, catalytic, magnetic properties of new obtained materials.
An important area of the work of the Laboratory is educational activities for the organization and guidance of scientific research and practical work of students of Lomonosov Moscow State University, Mendeleev University of Chemical Technology of Russia, National Research University Higher School of Economics, as well as graduate students of Zelinsky Institute of Organic Chemistry.
Broad opportunities and diverse prospects for collaborations should be also noted. In particular, the team has stable connections and fruitful cooperation with colleagues from Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS (Novosibirsk), Boreskov Institute of Catalysis SB RAS (Novosibirsk), Kurnakov Institute of General and Inorganic Chemistry (Moscow), Photochemistry Center RAS (Moscow), Arbuzov Institute of Organic and Physical Chemistry (Kazan), Favorsky Irkutsk Institute of Chemistry SB RAS (Irkutsk), Saint Petersburg State University (Saint Petersburg), Tomsk Polytechnic University (Tomsk), Florida State University (USA; prof. Igor Alabugin), Technische Universitat Chemnitz (Germany; prof. Heirich Lang), The University of Oxford (UK; prof. Philip Mountford), Zhejiang University (China; prof. Li Wang), Tsinghua University (China; prof. Mei-Xiang Wang).
The most important papers (published by researchers of the Laboratory affiliated with Chemistry Department of Lomonosov Moscow State University) for recent years:
1. "Supramolecular Organogels Based on N-Benzyl, N′-Acylbispidinols" // Nanomaterials — 2019 — 9(1) — 89. DOI: 10.3390/nano9010089. IF: 3.504. Q1
2. "Lanthanide complexes with 2-(tosylamino)-benzylidene-N-(aryloyl)hydrazones — universal luminescent materials" // Chem. Mater. — 2019 – 31(3) — 759-773. DOI: 10.1021/acs.chemmater.8b03675. IF: 9.89. Q1.
3. «On the design of new europium heteroaromatic carboxylates for OLED application» // Dyes and Pigments – 2019 – 130 – 107604. DOI: 10.1016/j.dyepig.2019.107604. IF: 3.572. Q1
4. «Isonitriles as Stereoelectronic Chameleons: The Donor-Acceptor Dichotomy in Radical Additions» // J. Am. Chem. Soc. – 2018 — 140(43) — 14272-14288. DOI: 10.1021/jacs.8b08513. IF: 14.357. Q1
5. «18F-radiopharmaceuticals based on the catecholamine group in the diagnosis of neurodegenerative and neuroendocrine diseases: approaches to synthesis and development prospects» // Russ. Chem. Rev. – 2018 – 4 – 350-373. IF: 3.836. Q1
6. “Stereocontrol in Preparation of Cyclopalladated Alkylaromatic Oximes and Evaluation of Their Stereoselective Esterase-Type Catalytic Activity” // Organometallics – 2017 –36(16) 3068–3075. DOI: 10.1021/acs.organomet.7b00410. IF: 4.051. Q1
7. “Tandem Intramolecular Cyclisation/1,3-Aryl Shift in N-(4,4-Diethoxybutyl)-1-Arylmethanimines (Kazan Reaction): Synthesis of 3-Benzylidene-1-Pyrrolines” // RSC Adv. – 2017 –7(80) – P. 50955-50960. DOI: 10.1039/c7ra11216e. IF: 2.936. Q1
8. “Europium 2-benzofuranoate: Synthesis and use for bioimaging” // Optical Mater. – 2017 –74 –191-196. DOI: 10.1016/j.optmat.2017.05.038. IF: 2.339. Q1
9. “Stereoelectronic Chameleons: The Donor-Acceptor Dichotomy of Functional Groups” // Chem. Eur. J. – 2017 – 23(14) – 3225-3245. DOI: 10.1002/chem201603491. IF: 5.160. Q1
10. “Copper−Bispidine Complexes: Synthesis and Complex Stability Study” // ACS Omega – 2016 – 1(5) – 854-867. DOI: 10.1021/acsomega.6b00237. Q1
