Leninsky Prospect, 47, Moscow
Phone: +7 499 137-29-44
Fax: +7 499 135-53-28

Laboratory for Studies of Homolytic Reactions (N13)

Head: D.Sc., Prof. RAS, Prof. D. Mendeleyev University of Chemical Technology, Terent’ev Alexander Olegovich. e-mail:terentev@ioc.ac.ru, alterex@yandex.ru; phone: +7 916 385 40 80

History of scientific school:

- 1964-2013 - Prof. Gennady Ivanovich Nikishin, Associate Memb. Acad. Sc.;

- 1934-1964 - Prof. Alexander Dmitrievich Petrov, Associate Memb. Acad. Sc.;

- Before this period – Prof. Vladimir Nikolayevich Ipatieff, General-Lieutenant of the Russian army, Member of the Russian Academy of Sciences. Head the research staff of the Universal Oil Products Company in Riverside, Illinois. Lecturer in Chemistry at Northwestern University.

 

Research areas.

  • Chemistry of aliphatic and alicyclic functionalized compounds.
  • Chemistry of peroxides.
  • Reactions with C-, O-, and S-centered radicals.
  • Oxidative coupling reactions.
  • Direct and indirect electroorganic synthesis.
  • Catalysis using transition metals.
  • Homogeneous and heterogeneous catalysis in oxidation reactions.
  • Compounds with antiparasitic, cytotoxic, and antimicrobial activity.
  • Agrochemistry.

Selected publications of last years:

Lapitskaya, M. A.; Vil’, V. A.; Daeva, E. D.; Terent’ev, A. O.; Pivnitsky, K. K. Alcoholysis of malonyl peroxides to give peracids. Mend. Comm. 2016, 26, 14-15.

Well-Known Mediators of Selective Oxidation with Unknown Electronic Structure: Metal-Free Generation and EPR Study of Imide-N-Oxyl Radicals.Igor B Krylov, Mykhailo O. Kompanets, Katerina V. Novikova, Iosip O. Opeida, Olga V. Kushch, Boris N. Shelimov, Gennady Ivanovich Nikishin, Dmitri O Levitsky, and Alexander Olegovich Terent'ev. J. Phys. Chem. A, 2016, 120 (1), pp 68–73. DOI: 10.1021/acs.jpca.5b10722

M.D. Vedenyapina, M.Yu. Sharipov, A.O. Terent’ev, A.M. Skundin, A.A. Vedenyapin, 2016, Zhurnal Fizicheskoi Khimii, 2016, Vol. 90, No. 2, pp. 290–293. [Russian Journal of Physical Chemistry A, 2016, Vol. 90, No. 2, pp. 475–478].

Alexander O. Terent’ev,  Vera A. Vil’, Evgenii S. Gorlov, Gennady I. Nikishin, Kasimir K. Pivnitsky,  Waldemar Adam. Lanthanide-catalyzed oxyfunctionalization of 1,3-diketones, acetoacetic esters, and malonates by oxidative C-O coupling with malonyl peroxides. JOC, 2016, 81, 810-823. DOI: 10.1021/acs.joc.5b02233

Alexander T. Zdvizhkov, Alexander O. Terent’ev, Peter S. Radulov, Roman A. Novikov, Viktor A. Tafeenko, Vladimir V. Chernyshev, Alexey I. Ilovaisky, Dmitri O. Levitsky, Fabrice Fleury, Gennady I. Nikishin, Transformation of 2-allyl-1,3-diketones to bicyclic compounds containing 1,2-dioxolane and tetrahydrofuran rings using the I2/H2O2 system, Tetrahedron Letters, 2016, 57, 949–952. http://dx.doi.org/10.1016/j.tetlet.2016.01.061

Alexander O. Terent'ev, Zhanna Yu. Pastukhova, Ivan A. Yaremenko, Roman A. Novikov, Dmitry V. Demchuk, Lev G. Bruk, Dmitry O. Levitsky, Fabrice Fleury, Gennady I. Nikishin. Selective transformation of tricyclic peroxides with pronounced antischistosomal activity into 2-hydroxy-1,5-diketones using iron (II) salts. Tetrahedron, 2016,72, 3421-3426. doi:10.1016/j.tet.2016.04.054

Alexander O. Terent’ev, Mikhail Yu. Sharipov, Alexey P. Glinuskin, Igor B. Krylov, Darya V. Gaidarenko, and Gennady I. Nikishin. Difference in a-thiocyanation of malonates, b-oxo esters and b-diketones with sodium thiocyanate and cerium(iv) ammonium nitrate. Mendeleev Communications, 2016, vol. 26, issue 3, p. 226-227. DOI: 10.1016/j.mencom.2016.05.001

Ashot V. Arzumanyan, Alexander O. Terent’ev, Roman A. Novikov, Valentin G. Lakhtin,  Michail S. Grigoriev, and Gennady I. Nikishin. Reduction of Organosilicon Peroxides: Ring Contraction and Cyclodimerization. Organometallics  2016, 35, 1667-1673.  DOI: 10.1021/acs.organomet.6b00129

Alexander O. Terent’ev, Zhanna Yu. Pastukhova, Ivan A. Yaremenko, Lev G. Bruk, and Gennady I. Nikishin. Promising hydrogen peroxide stabilizers for large-scale application: unprecedented effect of aryl alkyl ketones. Mendeleev Commun., 2016, 26, 329-331. DOI: 10.1016/j.mencom.2016.07.021

Ivan A. Yaremenko, Vera A. Vil’, Dmitry V. Demchuk and Alexander O. Terent’ev. Rearrangements of organic peroxides and related processes. Beilstein J. Org. Chem. 2016, 12, 1647–1748. doi:10.3762/bjoc.12.162

M.D. Vedenyapina, E.D. Strel’tsova, V.A. Vill’, A.O. Terent’ev, A.A. Vedenyapin. Solid Fuel Chemistry, 2016, Vol. 50, No. 5, pp. 306–309. (Khimiya Tverdogo Topliva, 2016, No. 5, pp. 34–37.). DOI: 10.3103/S0361521916050086

Alexander O. Terent'ev, Olga M. Mulina, Dmitry A. Pirgach, Dmitry V. Demchuk, Mikhail A. Syroeshkin and Gennady I. Nikishin Copper(I)-mediated synthesis of β-hydroxysulfones from styrenes and sulfonylhydrazides: an electrochemical mechanistic study. RSC Adv., 2016, 6, 93476-93485. DOI: 10.1039/C6RA19190H

Alexander O. Terent’ev, Olga M. Mulina, Dmitry A. Pirgach, Mikhail A. Syroeshkin, Alexey P. Glinushkin and Gennady I. Nikishin. Electrochemical synthesis of sulfonamides from arenesulfonohydrazides or sodium p-methylbenzenesulfinate and amines. Mendeleev Commun., 2016, 26, 538–539. DOI: 10.1016/j.mencom.2016.11.027

Ivan A. Yaremenko, Mikhail A. Syroeshkin, Dmitri O. Levitsky, Fabrice Fleury, Alexander O. Terent’ev. Cyclic peroxides as promising anticancer agents: in vitro cytotoxicity study of synthetic ozonides and tetraoxanes on human prostate cancer cell lines. Medicinal Chemistry Research, 2017, Volume 26, Issue 1, pp 170–179, DOI 10.1007/s00044-016-1736-2

Vera A. Vil’, Ivan A. Yaremenko, Alexey I. Ilovaisky and Alexander O. Terent’ev, Synthetic Strategies for Peroxide Ring Construction in Artemisinin, Molecules 2017, 22(1), 117; doi: 10.3390/molecules22010117

Gennady I. Nikishin, Nadezhda I. Kapustina, Lyubov' L. Sokova, Oleg V. Bityukov, Alexander O. Terent'ev. One-pot oxidative bromination – Esterification of aldehydes to 2-bromoesters using cerium (IV) ammonium nitrate and lithium bromide.Tetrahedron Letters, 2017, 58 (4), 352–354. http://dx.doi.org/10.1016/j.tetlet.2016.12.036

dos Passos Gomes, G., Yaremenko, I. A., Radulov, P. S., Novikov, R. A., Chernyshev, V. V., Korlyukov, A. A., Nikishin, G. I., Alabugin, I. V. and Terent'ev, A. O. (2017), Stereoelectronic Control in the Ozone-Free Synthesis of Ozonides. Angew. Chem. Int. Ed. 2017, 56, 4955-4959. doi: 10.1002/anie.201610699

Alexander O. Terent’ev, Vera A. Vil’, Evgenii S. Gorlov, Olga N. Rusina, Alexander A. Korlyukov, Gennady I. Nikishin, and Waldemar Adam. Selective Oxidative Coupling of 3H-Pyrazol-3-ones, Isoxazol-5(2H)-ones, Pyrazolidine-3,5-diones, and Barbituric Acids with Malonyl Peroxides: An Effective C-O Functionalization. Chemistry Select. 2017, 2, 3334-3341. DOI: 10.1002/slct.201700720

Margarita A. Lapitskaya, Vera A. Vil’, Ludmila L. Vasil’eva, Elena D. Daeva, Alexander O. Terent’ev and Kasimir K. Pivnitsky. Spontaneous reaction of malonyl peroxides with methanol. Mendeleev Commun., 2017, vol. 27, issue 3, p. 243-245. DOI: 10.1016/j.mencom.2017.05.008

Oleg V. Bityukov,Vera A. Vil’,Valentina M. Merkulova, Gennady I. Nikishin andAlexander O. Terent’ev. Silica gel mediated oxidative C-O coupling of β-dicarbonyl compounds with malonyl peroxides in solvent-free conditions. Pure and Applied Chemistry 2017 in press.

Mikhail A. Syroeshkin, Igor B. Krylov, Audrey M. Hughes, Igor V. Alabugin, Darya V. Nasybullina, Mikhail Yu. Sharipov, Vadim P. Gultyai, Alexander O. Terent’ev. Electrochemical behavior of N-oxyphthalimides: Cascades initiating self-sustaining catalytic reductive N-O bond cleavage. Journal of Physical Organic Chemistry 2017 in press.

 

Conferences organized by Institute:

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Important events:

Professor Mario Pargliaro Lecturing at Zelinsky Institute Prof Mario Pagliaro (Palermo Italy) gave two talks on June 8th and 9th.
Selective In-Situ Metal Azide Reactions Alexey Sukhorukov, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia, and colleagues studied the selective reactions of in-situ generated metal azides on N,N-bis(oxy)enamines. By combining readily generated bis(oxy)enamine substrates with sodium azide and one of a variety of metal salts (including Mg, Cu, Zn, Co, and Ni), the researchers showed that the metal cation selectively alters the mechanism to favor the formation of specific organoazide products.
On February 1st, Prof. Gleb Sukhorukov from the School of Engineering and Materials Science, Queen Mary, University of London, gave a lecture “Remote Controlled Delivery Nanosystems” at ZIOC.
“We can record up to one thousand spectra per day” Director of Zelinsky Institute about Devising New Molecules
Steep and Thorny Way of a Scientist in Russia Prof. Valentine Ananikov participated in the plenary panel discussion HR Challenge for the Society held in the framework of VII Russian National Congress of Young Scientists and Specialists on November 30 – December 1 2016 in MEPhI.
All Events »