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How the lockdown helped establish the mechanism of the reaction. Scientists of the ZIOC have discovered an unusual multicomponent process
The study of the mechanisms of organic reactions is often a long and difficult work. Particularly complex are the processes that result in the formation…
23 september 2022 г.
A method for automatic analysis of high-resolution mass spectra was developed in ZIOC
Mass spectrometry is a convenient, highly sensitive and reliable method for the analysis of complex mixtures, which is of key importance for the making…
19 september 2022 г.
Development of the catalysts for the selective hydrogenation of alkynes is continued in the ZIOC
The selective hydrogenation of acetylene to ethylene is an important industrial process. This is due to the fact that the original ethylene used to produce…
12 september 2022 г.
Researchers of the Zelinsky Institute discovered a new reactivity of pyridinium ylides
N-substituted ylides are versatile building blocks in organic synthesis, widely used to construct nitrogen-containing heterocycles. In particular, pyridinium…
8 september 2022 г.
ZIOC scientists have proposed an effective method for the synthesis of sterically hindered acridines
The processes occurring under photoredox catalysis conditions are currently being actively studied all over the world. Most often they proceed in mild…
![Researchers of the ZIOC published a review on [4+1]-annulation reactions](/cache/site/img-220905-09.f762be00.jpg)
5 september 2022 г.
Researchers of the ZIOC published a review on [4+1]-annulation reactions
Five-membered heterocycles containing one or more heteroatoms are important intermediates in organic synthesis on the way to bioactive and natural compounds.…
1 september 2022 г.
An unusual cyclization leading to functionalized isoxazolines was discovered at ZIOC
Isoxazolines are important representatives of five-membered nitrogen-oxygen heterocycles widely used in organic and medicinal chemistry. The isoxazoline…
24 august 2022 г.
Scientists from the Zelinsky Institute have developed an approach to the synthesis of important heterocyclic compounds
Functionalized derivatives of malonic ester are widely used in the synthesis of complex carbocyclic compounds. Their advantages are the ease of preparation,…
18 august 2022 г.
Scientists from the Zelinsky Institute have developed a stereoselective method for 1,2-cis-glucosylation
Fragments of 1,2-cis-linked glucose are a part of many biologically significant oligosaccharides. Traditionally, glucosyl donors containing a non-participating…
10 august 2022 г.
A new safe source of hydrazoic acid has been developed with the participation of ZIOC
In recent decades, alkyl azides have attracted increasing interest due to the possibility of their application both in organic synthesis and as high-energy…