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News

2020, September, 28

Scientists from Zelinsky Institute developed an effective method for the synthesis of an antagonist of hNK1 receptors - a promising agent for the treatment of gastrointestinal disorders associated with cancer chemotherapy

As part of research on the complete synthesis of bioactive pyrrolidine derivatives, the scientists of laboratory № 9 of ZIOC RAS developed an asymmetric full synthesis of Merck12-a2-2, its epimer at the C-12 position and their enantiomers with a total yield of 5% at 10 stages

2020, September, 21

The basis for drugs suppressing viruses and fungi was created in Zelinsky Institute

Despite the successful use of antibiotics and antifungal drugs in modern medicine, rising resistance to them has been increasingly observed in recent years. In this regard, there is a real need for innovative solutions aimed at stopping this problem and reducing the burden of infection resistant to existing drugs.

2020, September, 17

Scientists from ZIOC RAS developed an effective and atom-economical approach to highly functionalized vinylsulfides

Researchers from laboratory № 30 of ZIOC RAS succeeded in developing an efficient and atom-economical approach to the hydrothiolation of cyclopropylacetylenes. As a result, highly functionalized vinyl sulfides of the Markovnikov type were obtained.

2020, September, 14

Researchers from Zelinsky Institute developed an effective method of the synthesis of organofluorine compounds through alkenes difunctionalization

As part of the research by scientists of laboratory № 8 of Zelinsky Institute in the field of organofluorine chemistry, the process of fluoroalkylation-thiolation of alkenes under blue light irradiation was developed.

2020, September, 07

Scientists from Zelinsky Institute published a review on methods of oxidative sulfonylation of multiple bonds

The review, which was published by researchers of laboratory №13 of Zelinsky Institute, is devoted to recent achievements in the field of oxidative sulfonylation of multiple bonds with sulfonyl hydrazides, sulfinic acids and their salts, which are used as sulfonylation reagents in such transformations.

2020, September, 03

Researchers from ZIOC RAS developed a method for the synthesis of organometallic chalcogenides-based materials of various morphology

Researchers from ZIOC RAS discovered a new solid-phase reaction of carbon-sulfur bond formation with the use of metal-containing coordination polymers.

2020, August, 31

Scientists from Zelinsky Institute for the first time carried out oxidative coupling reaction with electrochemically generated N-oxyl radicals

Researchers from laboratory № 13 of Zelinsky Institute demonstrated that the generated from N-hydroxyphthalimide in undivided electrochemical cell radicals did not decompose, but selectively entered into an oxidative coupling with vinyl azides.

2020, August, 27

Results of the research by scientists from ZIOC RAS are featured on the cover of prestigious journal

The research carried out in laboratory № 13 of Zelinsky Institute in collaboration with colleagues from the National Center for Genetic Engineering and Biotechnology (Thailand) and the Macau University of Science and Technology (China), is featured on the cover of the top-rated international journal ChemMedChem.

2020, August, 24

Researchers from Zelinsky Institute developed a simple method for the synthesis of previously hardly available unsymmetrically substituted N-aryl oxalamides

Researchers from Laboratory № 22 of the Institute of Organic Chemistry have developed an easy synthetic route to unsymmetrically substituted N-aryl oxalamides using inexpensive and available 2,2'-biphenyldiamines, 2-chloroacetamides, sulfur, and water as starting compounds.

2020, August, 20

Promising high-energy compounds were synthesized by researchers from Zelinsky Institute

Over the last few decades, molecules representing a combination of aromatic nitrogen-oxygen heterocycles and energy functional groups, such as NO2, N3, NHNO2, N=N and N=N(O), as substituents have attracted considerable interest in the search for new explosives. Researchers from Laboratody № 19 of Zelinsky Institute are actively involved in the research in this direction.

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Congratulations! Valentine Ananikov has been elected to Academia Europaea! The European Academy of Sciences (Academia Europaea) was founded in 1988. It unites about four thousand globally acknowledged experts in mathematics, medicine, natural sciences, humanities, law, economy, and social and political sciences from many countries of Europe. Among its members are also European scientists who live in other regions of the world. Currently, it includes seventy two Nobel laureates and it should be highlighted that many of them were elected to the Academy before winning the Prize.
Professor Mario Pargliaro Lecturing at Zelinsky Institute Prof Mario Pagliaro (Palermo Italy) gave two talks on June 8th and 9th.
Selective In-Situ Metal Azide Reactions Alexey Sukhorukov, N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia, and colleagues studied the selective reactions of in-situ generated metal azides on N,N-bis(oxy)enamines. By combining readily generated bis(oxy)enamine substrates with sodium azide and one of a variety of metal salts (including Mg, Cu, Zn, Co, and Ni), the researchers showed that the metal cation selectively alters the mechanism to favor the formation of specific organoazide products.
On February 1st, Prof. Gleb Sukhorukov from the School of Engineering and Materials Science, Queen Mary, University of London, gave a lecture “Remote Controlled Delivery Nanosystems” at ZIOC.
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