News
10 november 2022 г.
Scientists from the ZIOC proposed a "reverse" strategy for the formation of C-O bonds
Nucleophilic substitution at the carbon atom is a fundamental organic transformation. In its textbook version, a nucleophilic reagent replaces a carbon-bonded…
7 november 2022 г.
Researchers of the Zelinsky Institute studied the cytotoxicity of protic ionic liquids
At present, due to their unique electrochemical, solvation, and catalytic properties, ionic liquids are widely used in chemistry, biotechnology, biochemistry,…
3 november 2022 г.
A new class of high-energy compounds has been obtained at the Zelinsky Institute
The development of new functional organic materials remains one of the urgent problems of modern chemistry and materials science. High energy materials…
31 october 2022 г.
Scientists from ZIOC have studied the reaction of donor-acceptor cyclopropanes with 5-aminopyrazoles
Donor-acceptor cyclopropanes are polyfunctional compounds exhibiting a wide spectrum of reactivity. The Laboratory of Directional Functionalization of…
28 october 2022 г.
Researchers of the Zelinsky Institute published a review on the use of supercritical carbon dioxide for the production of functional materials
The negative impact of human activities on the environment is becoming more and more obvious. In this context, in recent years, considerable attention…
24 october 2022 г.
With the participation of the Zelinsky Institute N-fluoroalkylpyrazolyl-substituted nitronylnitroxides were obtained and their inherent structure-property correlations were revealed
The introduction of a fluorine atom into a paramagnetic molecule changes the solubility of the compound, increases its volatility, significantly affects…
21 october 2022 г.
Scientists of the Zelinsky Institute have obtained new high-energy salts based on triazole and furoxan
One of the most promising classes of high-energy materials are structures containing several nitrogen-containing heterocyclic fragments. One of the key…
17 october 2022 г.
Scientists from the Zelinsky Institute have synthesized photostable analogs of combretastatin A4 with antiproliferative activity
A number of medications are very sensitive to light and are subjected to significant photodegradation. As a result, there is a decrease in the quality…
13 october 2022 г.
An effective method for the synthesis of a promising neurokinin receptor antagonist has been developed at the ZIOC
Neurokinin receptor antagonists are an important component of the complex of chemotherapeutic agents used to treat cancer. Most often, preparations of…
7 october 2022 г.
ZIOC scientists analyzed the diversity of fungal carbohydrates
Statistical analysis of the structural diversity of carbohydrates using the methods of glycoinformatics makes it possible to identify and systematize the…